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"Making cigarettes and other combusted tobacco products minimally addictive or nonaddictive would help save lives." The FDA funded a randomized trial published in 2018 that found "reduced-nicotine cigarettes versus standard-nicotine cigarettes reduced nicotine exposure and dependence and the number of cigarettes smoked." Another FDA-funded study found that, if a nicotine reduction policy were enacted in 2020, it could result in more than 33 million people not becoming regular smokers, and prevent more than 8 million deaths from tobacco-related illnesses by 2100

Within months, coughing and shortness of breath decrease

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Lung scarring: The chemical diacetyl (2,3-butanedione) is used in some vape flavorings, which can cause bronchiolitis obliterans (BOS), also called popcorn lung, which causes permanent lung scarring