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The sulfhydryl group is the most important functional group of reduced glutathione

In Gram-negative bacteria, eleven protein (type I-XI 1,2,3,4,5 ), one nucleic acid (type IV 6 ), and three carbohydrates (Wzx/Wzy, ABC transporter, and synthase-dependent 7 ) secretion systems have been described

In addition, a slew of emerging classes of TXNRD inhibitors have surfaced, encompassing diverse agents such as natural products, metal complexes, and nitro (hetero) aromatic compounds [240]

NaBPC157's protection was still evident in the capsaicin treated models (either treated as adults or as neonatals) in all of these assays