Inhibition of LDHA/lactylation (oxamate) or PDGFR (axitinib) suppressed malignant phenotypes and slowed PDX growth, with the combination producing the strongest tumor regression and reduced pulmonary metastasis, supporting co-targeting of lactylation and PDGFR in VHL-mutant ccRCC [97]
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This review describes the recent studies on the enrichment of Se-containing plants in particular Se accumulation and speciation, their functional properties related to human health, and future perspectives for developing Se-enriched foods
Bolton WD, Hofstetter WL, Francis A, Correa AM, Ajani, JA, Bhutani B, Erasmus JJ, Komaki R, Maru D, Mehran RJ, Rice DC, Roth JA, Swisher SG , Vaporciyan AA, Walsh GL, Weaver J, Rhines L