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Flow cytometry analysis of cumulus cells Cumulus cells were collected from mature COCs and examined using a FlowSight Imaging Flow Cytometer (Amnis, Merck-Millipore, Germany) as previously described [28]

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If semaglutides gastric-emptying effect attenuates over time (as is characteristic of long-acting GLP-1 agonists) while cagrilintides central satiety persists, the durable benefit of the combination may lean more on appetite suppression than on sustained gastric slowing again pushing the postprandial gastric framing toward the acute phase of treatment rather than the maintenance phase