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4 Advances in Drug Application to Improve Cardio-Cerebrovascular by Interfering Ferroptosis At present, the World Health Organization is committed to the global prevention, management and monitoring of CCVDs, to identify potential mechanisms and effective therapeutic drugs, in order to reduce the incidence, prevalence and mortality of CCVDs (Zhang X

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The mitochondrial enzymes that are significantly reduced in a mouse model that develops type 2 diabetes progressively include PC, cICD, NADH dehydrogenase, citrate synthase and ATP synthase [80]

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