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Nicotine exposure during adolescence can be long-lasting and may result in lower attention, impulse control, mood disorders, and addiction Some e-cigarette products can contain as much nicotine as a pack of 20 regular cigarettes E-cigarettes can cause unintended injuries from fires and explosions caused by defective e-cigarette batteries

A few cross-sectional studies suggest an association between vaping and kidney damage (albuminuria, reduction in estimated glomerular filtration rate) in adolescents and young adults