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Dysregulated iron metabolism not only promotes ferroptosis but also disrupts essential metabolic processes required for tissue repair, highlighting its role in ARDS progression ( 4.3 Fibrosis and long-term outcomes The chronic inflammation and unresolved ferroptosis associated with ARDS contribute significantly to lung fibrosis and long-term complications

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J Cardiovasc Pharmacol 46:646652 Grimsrud PA, Xie H, Griffin TJ, Bernlohr DA (2008) Oxidative stress and covalent modification of protein with bioactive aldehydes