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Lugrin J, Ciarlo E, Santos A, Grandmaison G, dos Santos I, Le Roy D, Roger T (2013) The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock

Defective human spermatozoa is characterized by the presence of large amounts of DNA damage, which is largely oxidative in nature and closely associated with defects in spermiogenesis, which are further associated with reduced fertility, increased rates of miscarriage, and an enhanced risk of disease in the offspring

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[28] As with gastric cancer, these cancers with the lowest levels of FOXO4 also had the lowest levels of E-cadherin and highest levels of vimentin, consistent with FOXO4 acting as a suppressor of the EMT phenotype