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However, further modifications such as the inclusion of serum or -proteins 11,17,19,88,89,90 , adjusting physiologically relevant carbon sources and their concentrations 91,92,93 , or the co-cultivation with common commensals to mimic the host-environment 94,95,96,97,98 can help to further improve translational capacity
Furthermore, this study showed that at the same concentration, the efficacy remained stable over time, as the percentage of dead bacterial cells at the highest DJK-5 concentration (10 g/mL, 6.5 M) was similar between 1 day (8591%) and 3 days (8791%) in all biofilms of the three donors and in all cases [28]
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Antioxidant and Anti-inflammatory Action: It scavenges free radicals, blocks iron-induced oxidative damage, and downregulates pro-inflammatory cytokines, calming systemic inflammation
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