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A 2019 meta-analysis of 94 publications reported that 95.1% of studies with no financial conflicts-of-interest (COI) found potential harm caused by e-cigarettes, compared to just 7.7% of studies funded by the tobacco industry 39

Oral cancer is more common in men, perhaps because men are more likely to use tobacco and alcohol than women

Because smoking is so popular, the total health benefits from tobacco harm reduction dwarf those from any other area of HR

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