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This stabilizes the transcription factor BACH1, which subsequently upregulates angiogenesis-related factors, including PDGFB, EGFR, FGF2, and FGFR1, ultimately driving vascular regeneration

In mouse OCTN3/SLC22A21, a sodium-independent carnitine transporter absent in humans 47,48 , the dual glutamine motif is replaced with a dual histidine motif, which is the only significant difference in residues between the carnitine/sodium sites of hOCTN2 and mOCTN3 (78.7% identity, Supplementary Fig