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Overexpression of TLR7 and TLR8 in females can lead to stronger immune responses and a higher prevalence of autoimmune diseases (40), like systemic lupus erythematosus (41)

Bajko, J., Duguid, M., Altmann, S., Hurlbut, G

2.2 Mechanism and causes Muscle functionality and contractility can suffer impairment either at or beyond the neuromuscular junction, termed peripheral fatigue, or proximal to it, referred to as central fatigue

When treatment is thoughtful, science-guided, and accessible, platforms like Alan Health can help individuals take meaningful steps toward feeling their best." If you're constantly tired despite getting enough sleep, low B12 could be part of the reason