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Rossignol D, Frye RE

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Ultraviolet radiation can contribute to: oxidative stress premature skin aging uneven skin tone cellular damage Using sunscreen and limiting excessive sun exposure helps protect skin cells from these effects

Emerging research directions include investigation of senescence heterogeneity and tissue-specific senescent cell populations, with FOXO4-DRI serving as a tool for studying how different senescent cell types contribute to various pathological processes