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revealed the grievous connection between oxidative stress, pyroptosis, inflammation response, and xenobiotic metabolism in the myocardium of TMT-treated rats by String database analyzing the proteome interaction protein [206]

1c,ii), but because the sidechain of Tyr78 maintains a network of hydrogen bonds stabilizing the 1-1 loop interactions with helices 2 and 10, mutation to His78 will lead to a disruption of the hydrogen bond network, stability, and dynamics

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