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[Made by author on BioRender] Breaking down the BBB Structure Discovered at the beginning of the 20th century by experiments led by Paul Ehrlich and then Edwin Goldman, the biological components of the BBB have been identified over the last century

Safety outcomes included 90-days mortality and symptomatic haemorrhagic transformation (sICH)

Weight loss typically accelerates during this period, with most researchers reporting 4-8% body weight reduction by week 12

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