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Severe cases can lead to dementia and psychosis

Currently, Triluma (hydroquinone 4%, tretinoin 0.05%, fluocinolone acetonide 0.01%) is the only triple combination therapy approved in the USA for melasma [6, 205]

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In addition to its status as an antioxidant, glutathione is also a peptide composed of three amino acids: cystine, glutamic acid and glycine