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The major risk factors for HCC include cirrhosis from chronic HBV or HCV infection, alcohol use, nonalcoholic fatty liver disease, hereditary hemochromatosis, other causes of liver injury such as 1-antitrypsin deficiency, autoimmune hepatitis, primary biliary cirrhosis, and tyrosinema

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Peptide therapy is entering that conversation some of it warranted by strong clinical evidence, some by genuine mechanistic promise, and some driven by a patient community that has run ahead of the research