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Anecdotal reports from Phase 2 participants suggest that nausea severity is higher when dosing occurs in the early morning on an empty stomach, possibly because fasting amplifies the compound's gastric-slowing effect

The clinical development program was discontinued due to insufficient weight loss efficacy rather than safety concerns

However, with limited resources there is an inequality in access to these treatments across the globe, particularly in developing countries

While acute wounds generally heal through an orchestrated immune response that supports tissue repair, chronic wounds are marked by immune dysregulation and an inability to transition from inflammation to healing [17]