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WADA has determined that these routes of administration result in a significant level of glucocorticoids circulating in the blood, which has the potential to result in performance enhancement or cause harm to health

31 Following vaccination in people with multiple sclerosis taking DMF, one study found no decrease in the ability to mount an immune response

doi: 10.1038/s41430-018-0381-x

Abbreviations Akt: Protein kinase B CDKs: Cyclin-dependent kinases ERK: Extracellular-signal-regulated kinases IB: Inhibitor of NF-B IKK: IB kinase IGF: Insulin-like growth factor IL-1: Interleukin-1 IL-2: Interleukin-2 IL-6: Interleukin-6 JNK: C-Jun N-terminal kinases LPS: Lipopolysaccharides MAPK: Mitogen-activated protein kinase MREs: Metal-response elements MT: Metallothionein MTF-1: Metal-regulatory transcription factor 1 NF-B: Nuclear factor kappa B NK cells: Natural killer cells PI3K: Phosphatidylinositol 3-Kinase ROS: Reactive oxygen species SOD: Superoxide dismutase Sp1: Specificity protein 1 TNF-: Tumor necrosis factor-alpha TRAF2: TNF receptor-associated factor 2 ZnT1: Zinc transporter 1 ZnT2: Zinc transporter 2 ZnT3: Zinc transporter 3 ZnT4: Zinc transporter 4 References Sun XR, Xu S, Liu TJ, Wu JW, Yang J, Gao XJ