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doi: 10.1093/pcmedi/pbae001 209 DengWFengXLiXWangDSunL

After its synthesis, GSH is delivered to some intracellular compartments, including mitochondria, endoplasmic reticulum, nucleus, and to the extracellular space (e.g., blood plasma and bile) for utilization by other cells and tissues ( In contrast to GSH synthesis, which occurs intracellularly, GSH degradation occurs exclusively in the extracellular space, and in particular, on the surface of cells that express the enzyme -glutamyl transpeptidase (also called -glutamyl transferase, GGT

The concentrations corresponding to the linear relationship were (50250 g/mL, 1575 g/mL, and 210 g/mL) for l-glutathione, n-acetyl l-cysteine, and Vitamin-C, as mentioned in Tables 4, 5 and 6 respectively