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It is still too early to draw definitive conclusions, but the numerous ongoing clinical trials, including the cardiovascular safety trial versus an active comparator (dulaglutide), the first of its kind, will provide us shortly with important confirmations

The clinical implication of our findings is to use TdGSH to prevent progressive loss of -cell mass in diabetic patients, who have more glycaemic variabilities because of the vicious metabolic memory obtained from the disease, and to block the development of diabetic complications

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