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AOD 9604 is a modified peptide fragment of human growth hormone (HGH), specifically a stabilized version of amino acids 176191 of the HGH molecule

The compound demonstrates exceptional target selectivity, with no inhibition of related methyltransferases (DNMT1, PRMT3, COMT) or NAD+ salvage enzymes (NAMPT, SIRT1) at concentrations up to 600 M

Studies reveal enhanced fatty acid oxidation, increased energy expenditure, and improved metabolic efficiency through direct NNMT inhibition, positioning it as breakthrough tool for investigating obesity mechanisms without appetite suppression

HGH Fragment 176-191 is the more general scientific name