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doi: 10.1016/j.gendis.2021.02.009

Moreover, PPIs can disrupt the gastric acid barrier and intestinal microecology and cause exogenous bacterial invasion, which can lead to infectious diseases of the gastrointestinal and biliary tracts and SIBO

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Pen Dosage Chart Dosage & Protocols Variations Standard Research Protocol Dose: 0.1 0.3 mg (= 412 clicks) Duration: 2 4 weeks Frequency: Once daily, prior to rest phase Cycle Interval: 2 weeks off before repeating Goal / Description: Baseline protocol used in sleep architecture and circadian rhythm research models