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Despite their potential, polyphenols remain underutilized in functional foods and dietary supplements due to several physicochemical properties, including low epithelial permeability, poor solubility in gastrointestinal fluids, structural modifications during digestion, and limited oral bio-accessibility (128, 129)

In laboratory research, MOTS-C is studied to: Explore AMP-activated protein kinase (AMPK) pathway activation in vitro

At different stages of the cycle, some of the water is intercepted by humans or other life forms for drinking, washing, irrigating, and a large variety of other uses