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Clostridium butyricum and its metabolite butyrate promote ferroptosis susceptibility in pancreatic ductal adenocarcinoma

The peptide selectively binds copper over other divalent metal ions present in physiological conditions, and the resulting complex is stable across a relevant pH range

In another study, significantly higher ratios of oxidized to reduced glutathione and significantly lower activities of glutathione peroxidase were detected in whole blood and peripheral mononuclear cells in hypertensive patients compared to normotensive volunteers re, a finding supported by another study reporting significantly lower GSH and higher GSSG values in mononuclear cells from hypertensive subjects compared to controls (19)