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Spectrum of Toxins: While PM2.5 is a primary concern, cigarette smoke contains unique carcinogens like tobacco-specific nitrosamines, and urban air contains its own cocktail of ozone, nitrogen oxides, and heavy metals

In fact, Gong et al 4 reported that the histological effects of 3-4 marijuana cigarettes on the airway were comparable to smoking 20 tobacco cigarettes

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The loss of the Y chromosome was dependent on a mans reliance on tobacco