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8 Healthy Ageing Research Healthy ageing research has identified progressive declines in collagen production, extracellular matrix integrity and regenerative capacity as characteristic features of ageing tissues

Intriguingly, characterization of the transcriptional response to cysteine deprivation has revealed glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1) as the most highly induced gene 6

The impact of endotoxins and leaking antigens on detoxification mechanisms can be significant

706 Metformin therapy activates the Nrf2 signaling pathway and improves SCI-induced motor dysfunction by inhibiting ferroptosis and the inflammatory response