Carefully review trial quality and endpoints before adopting
During the review, the committee will likely consider: The extensive body of published research on GHK-Cu (decades of studies) Safety data for both injectable and topical routes The clinical rationale for copper peptide therapy in anti-aging and wound healing Quality control considerations for compounding GHK-Cu formulations Public comments from patients, dermatologists, anti-aging practitioners, and pharmacies Given GHK-Cu's long history of use and substantial research base, many in the peptide therapy community are cautiously optimistic about a positive PCAC recommendation particularly for the topical route
Comprehensive lab panel Estradiol, progesterone, testosterone (total and free), FSH, LH, DHEA-S, cortisol, thyroid markers
AIs can be divided into two groups based on their chemical structure: steroidal (analogs of androstenedione, exemestane, formestane, and testolactone), which provide irreversible aromatase inhibition, and non-steroidal (anastrozole and letrozole), which provide reversible inhibition (Ahmad, 2015)