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[15] Serious but infrequent events-such as angioedema, bronchospasm, hypotension, or urticaria-reflect IgE-mediated hypersensitivity and may require desensitization or substitution with hydroxocobalamin

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Midis medical experts currently recommend turning to other evidence-informed solutions instead, depending on what outcome youre trying to achieve: Boost healing or speed up recovery: Optimize local therapies and support, such as physical therapy, expert-recommended cooling and warming approaches, and functional support braces as your mainstay