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After chronic (18 mo) administration of the pineal gland preparation epithalamin the amount of stromal cells-precursors, CD4+ and Mac-1(+)-cells in old bone marrow increased, improved the migration of T-cell precursors from bone marrow to thymus and their proliferative potential

The peptide's effects were mediated through the downregulation of miR-339-5p expression, which was found to be part of the p38 MAPK pathway

The parallel decline in endogenous GHK-Cu levels is suggestive, though causation has not been established

Adjusted odds ratios (ORs) with 95% confidence intervals (CIs) were calculated for all predictors