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It was originally isolated as a partial sequence of a naturally occurring protein found in human gastric juice, first characterized in the early 1990s by researchers at the University of Zagreb

The peptide solution may look identical, but protein aggregation and hydrolysis are already underway

Glucagon-like peptide-1 (GLP-1) agonists, initially indicated for treatment of T2D, are the newest FDA-approved AOMs

it is naturally occurring, nontoxic, and is active at a very low nanomolar concentration.11 Another piece of research described GHK-Cu as a safe, inexpensive, extensively studied compound.3 These conclusions primarily apply to topical GHK-Cu, but even with injectables, the lack of serious adverse events in animal subjects points to a general tolerability regardless of the route of administration