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While further studies will be required to establish clinical relevance, the findings provide a rational foundation for advancing antioxidant nanocarriers as potential candidates for future development in the management of radiation-related skin toxicity

129131 The administration of pharmacological inhibitors targeting inflammasome components, such as NLRP3 or caspase-1 inhibitors, mitigates APAP-induced liver injury in preclinical models, highlighting the pivotal role of inflammasomes in modulating hepatic inflammation and damage

However, the choroid plexuses are disproportionately larger in the developing brain (Johansson et al., 2008) and transfer proteins across their epithelial cells (see below)

This recent original paper presents data on a potential new treatment for WD, which may address some unmet needs associated with currently available therapies