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Cellular protection: Binds and neutralizes excess metal ions (such as zinc or copper), which reduces free radical formation

ChemSusChem 16 , e202202361 (2023)

The authors reported that the 90 minute exercise protocol increased intestinal lymphocytes phosphatidylserine concentration, mitochondrial membrane depolarization, and decreased intracellular glutathione concentration (p 2.0.CO;2

Therefore, the homocysteine level may not rise enough to the abnormal range in a person with Down syndrome with a decrease in vitamin B12 or folate activity