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Despite the robust preclinical data, human clinical trials remain scarce

Additionally, patients on chemotherapy should consult with their oncologist prior to using glutathione, as it may interfere with the oxidative stress mechanisms that some chemotherapeutic agents rely on to exert their cytotoxic effects

Pentoxifylline, an inhibitor of TNF- synthesis, was initially reported to reduce short-term mortality in patients with AH, primarily by lowering the risk of hepatorenal syndrome [30]

Supplementing NAC-alone does not provide glycine, and only GlyNAC provides both the glycine and cysteine needed for GSH synthesis