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To characterize the interaction between GLR3.3 and GSH, the predicted structure of GLR3.3 was used to perform molecular docking

The moment glutathione gets oxidizes to glutathione disulfide (GSSG), the game changes entirely

Plant Sci 180:575583 Dubreuil-Maurizi C, Poinssot B (2012) Role of glutathione in plant signalling under biotic stress

The increased oxidative stress seems to be the second hit in the progression from NAFL to NASH: the increase in ROS and consequently in lipid peroxidation has been associated to hepatocellular damage, inflammation, and eventual fibrosis due to the activation of hepatic stellate cells