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CDC WONDER On-line Database, Natality public-use data 2007-2014, 2016

Vape pen use may also weaken the lungs' immune defenses and increase the risk of infections with pathogens, including the influenza virus and Streptococcus pneumoniae bacteria, according to a 2022 review published in the journal Cureus

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44,45 These mtROS not only directly cause oxidative damage to DNA, lipids, and proteins but also act as signaling molecules to activate inflammation-related pathways such as the NLRP3 inflammasome and NF-B