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10.1016/j.phymed.2024.155554 Summary Keywords Chinese medicine, natural metabolites, CVDs, flavonoids, alkaloids, saponins Citation Liu X, Zhang W, Miao X and Hu Y (2025) Natural metabolites used in traditional Chinese medicine for cardiovascular diseases: pharmacological mechanisms, evidence, and future directions

However, similar to other metabolites, the physiology of TMAO is complex, as TMAO acts on multiple organs, with evidence of beneficial effects in the brain

Delivery of circ-Snhg11 from hypoxia-pretreated adipose-derived stem cell-originating exosomes (ADSC-HExo)-embedded GelMA hydrogels (GelMA-HExo) can improve EC survival and function by activating miR-144-3p/NFE2L2/HIF1 signaling, implicating the role of ADSC-Exos in diabetic wound healing (231)

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