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A roll-up ( hand-rolled cigarette using loose or shag tobacco ) typically contains 8 mg to 20 mg of nicotine, with an estimated 1 mg to 2 mg absorbed

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In terms of actual nicotine absorption, our clinical studies have consistently shown that Juul use at five percent strengths results in an average nicotine uptake that is similar to, but lower in concentration than a commercial reference combustible cigarette

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