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Another essential component concerns pharmacokinetics (PK) and pharmacodynamics (PD)

These data suggest that the genetic features of specific enzymes of the glutathione antioxidant system and their control of oxidative and nitrosative stresses throughout the lifespan highlight their likely involvement in defining the fate of normal aging, particularly in the CNS

[120] However, animal studies have limitations in their applicability to human pregnancy, and the doses used in research settings may not reflect typical clinical use patterns

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