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Kuo, H.-C

Over time, chronic inflammation can quietly affect nearly every system in the body contributing to fatigue, brain fog, hormone imbalance, weight gain, digestive issues, joint pain, accelerated aging, poor recovery, and increased risk for cardiovascular disease, autoimmune disorders, insulin resistance, and neurodegenerative disease

In the interest of identifying all sources of inflammation, I believe it is crucial to test everyone with chronic illness and immune dysregulation for leaky gut syndrome.

However, increased GSNO levels have been observed in inflammatory states and subsequent induction of inducible nitric oxide synthase (iNOS), which is also related to hypertension (32)