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However, the native hormone is unstable and prone to aggregation, limiting its therapeutic use

Progress and challenges in sporadic late-onset cerebellar ataxias

While this rapid evolution toward multi-agonist strategies and oral formulations promises enhanced efficacy, tolerability, and adherence, generating robust long-term safety and efficacy evidence remains imperative

In older adults, GlyNAC supplementation has been studied for effects on glutathione levels, oxidative stress, mitochondrial function, inflammation, muscle strength, and cognition.34 While the results have generated significant interest, it's not yet clear how much of the observed benefit comes from NAC itself versus the combination of NAC and glycine