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The three amino acids in KPV (lysine-proline-valine) represent the C-terminal sequence responsible for most of alpha-MSHs anti-inflammatory activity

The tolerogenic mechanism is elegant: by presenting histone epitopes in a context that promotes regulatory rather than effector T cell responses, these peptides essentially re-educate the immune system to tolerate its own nuclear components

As much as these injections help improve the health of ones skin and promote anti aging benefits, there are safety issues plus cost although provider competence must never be ignored