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The action of the virus and the human defense mechanisms activate anti-viral processes, causing hyperinflammation, which then activates neutrophils, monocytes, and platelets and results in the activation of the coagulation cascade, possibly leading to intravascular thrombosis (Bermejo-Martin et al., 2020

Levels below 80 ng/ml can be harmful, especially after age 75

In the SURMOUNT-1 trial, tirzepatide produced average weight loss of 15-22.5% of body weight over 72 weeks depending on dose

FIGURE 2 6 Conclusion and future perspectives Therapeutic approaches to address oxidative stress typically involve upregulating antioxidant signals such as NRF2, administering exogenous antioxidants, supplementing trace elements or nutrients, and implementing environmental interventions (Forman and Zhang, 2021)