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The observed decrease in MCP-1 staining intensity suggests that intranasal administration of GHK-Cu in transgenic 5xFAD mice had a reducing effect on the AD-induced inflammatory phenotype and could serve as a reliable prototype to study drugs that slow or stop progression of AD [40]

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(5) K P Lesch 1, E Widerlv, R Ekman, G Laux, et al (1988) Delta sleep-inducing peptide response to human corticotropin-releasing hormone (CRH) in major depressive disorder