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The working mechanism of this combined antioxidant formulation has been described as follows: The formulation works primarily through antioxidant synergy

In addition, the authors thank Lindsay Uglow of Spirit Medical Communications Group Limited for medical writing and editorial assistance (funded by Novo Nordisk A/S) and Christin Lth Hertz of Novo Nordisk for reviewing the manuscript

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The most clinically relevant efficacy data came from METAOD005, a 12-week randomized double-blind placebo-controlled study