Youssef ME, Moustafa Y, Abdelrazek H (2020) Molecular mechanisms of 7-nAchR-mediated anti-inflammatory effects
It achieves these remarkable effects by promoting the synthesis of vital skin proteins such as elastin and collagen, enhancing skin elasticity and firmness
Decreased expression of Opa1, Mfn1, and Mfn2, along with increased expression of Drp1 in podocytes cultured under high glucose conditions, mitigated excessive mitochondrial fission and cellular damage in podocytes when thromboxane/prostaglandin receptor (TP receptor) was silenced ( in vitro studies found that overexpression of CAMK1 inhibited mitochondrial fission and mitigated high-glucose-induced apoptosis in HK-2 cells ( 2.4 Mitophagy and DN The process of mitophagy involves the selective encapsulation and degradation of damaged or dysfunctional mitochondria by cells through the autophagy mechanism, thereby maintaining mitochondrial and intracellular homeostasis ( In a study of DN, the aldose reduction inhibitor WJ-39 demonstrated efficacy in improving renal tubular morphology and inhibiting renal fibrosis in DN rats by inhibiting the activation of the polyol pathway
Kumar D, Datta R, Sinha R, Ghosh A, Chattopadhyay S (2014) Proteomic profiling of -ECS overexpressed transgenic Nicotiana in response to drought stress
