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17 Several 17th century herbal books refer to it as Nicotiana minor

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He also added, Its almost a pointless exercise talking to FDA because they never give you clarity. When I asked the FDA the same question about synthetic nicotines status as a tobacco product, the agency replied, These products will be evaluated on a case-by-case basis. Given that the FDA has asserted it can regulate even vaping liquids that contain no nicotine though, it does not seem poised to turn a blind eye to synthetic nicotine on technical grounds

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