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Participants Thirteen subjects with DSPS, recruited via flyers, advertisements, and referrals from the Sleep Clinic, completed this study

Additionally, capecitabine is well known to cause hand-foot syndrome (palmar-plantar erythrodysesthesia) , which, although classified dermatologically, shares mechanistic overlap with GI toxicity due to the drugs activation in high perfusion areas

Advanced techniques, including de novo synthesis, proteomic analysis, and bioinformatics, further aid in their design, optimization, and functional characterization

According to the NIH, there is no cure or treatment for this condition other than managing the illnesses that accompany it