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Kong et al., similarly uncovered synergy between a complex I inhibitor and a mito-antioxidant in cancer cells, suggesting their ability to reduce mitochondria-derived H 2 O 2 levels as a potential mechanism of action ( 2 O 2 levels increased after 24 hours of (M+D)/2 and (M+D+V)/3 treatments
In several patients with BCS, protein C deficiency has also been associated with an underlying myeloproliferative disorder
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Materials and methods Ethic statements The animal studies were carried out in strict accordance with the Detailed Rules for the Administration of Animal Experiments for Medical Research Purposes issued by the Ministry of Health of the Peoples Republic of China and were approved by the Animal Experiment Administration Committee of The Fourth Military Medical University
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