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The radiotracers used in PET imaging emit positrons, which will typically travel a few millimeters before colliding with an electron in the surrounding tissue, resulting in the emission of two 511 keV photons in opposite directions that are then detected by PET detectors oriented around the patient

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The authors performed a systematic review and meta-analysis including 9017 non-Hispanic black and white smokers with CHRNA5 rs16969968 and CHRNA3 rs1051730 genotypes in 40 clinical trials with active arms (bupropion, varenicline, nicotine replacement therapy, or a combination of therapies) versus placebo